The University of Iowa


Improving natural product research translation: From source to clinical trial.

Sorkin BC, Kuszak AJ, Fukagawa NK, Hoffman FA, Jafari m, Barrett B, Brown PN, Bushman FD, Casper S, Chilton FH, Coffey CS, Ferruzi MG, Hopp DC, Kiely M, Lakens D, MacMillan JB, Meltzer DO, Pahor M, Paul J, Pritchett-Corning K, Quinney SK, Rehermann B, Setchell K, Sipes NS, Stephens JM, Taylor DL, Tiriac H, Walters WA, Xi D, Zappala G, Pauli GF.
FASEB Journal. 2019 Dec 10; 34 (1) 41-65.

Clinical and dopamine transporter imaging characteristics of non-manifest LRRK2 and GBA mutation carriers in the Parkinson's Progression Markers Initiative (PPMI): A cross sectional study.

Simuni T, Uribe L, Cho RH, Caspell-Garcia C, Coffey CS, Siderowf A, Trojanowski JQ, Shaw LM, Seibyl J, Singleton A, Toga AW, Galasko D, Foroud T, Tosun-Turgut D, Poston K, Poewe W, Weintraub D, Mollenhauer B, Tanner CM, Kieburtz K, Chahine LM, Reimer A, Hutten S, Bressman, Marek K, on behalf of the PPMI Investigators.
Lancet Neurology. 2019 October 31; 19 (1) 71-80.

Feasibility and safety of lumbar puncture in the Parkinson's Disease research participants: Parkinson's Progression Marker Initiative (PPMI).

Prakash N, Caspell-Garcia C, Coffey CS, Siderowf A, Tanner CM, Kieburtz K, Mollenhauer B, Galasko D, Merchant K, Foroud T, Chahine LM, Weintraub D, Casaceli C, Dorsey R, Wilson R, Herzog M, Daegele N, Arnedo V, Frasier M, Sherer T, Marek K, Simuni T, on behalf of the Parkinson's Progression Markers Initiative Steering Committee, Study Cores, Site Investigators, Coordinators, and Industry & Scientific Advisory Board.
Parkinsonism & Related Disorders. 2019 May; 62 201-209.

Final Results of the RHAPSODY Trial: A Multi‐Center, Phase 2 Trial Using a Continual Reassessment Method to Determine the Safety and Tolerability of 3K3A‐APC, A Recombinant Variant of Human Activated Protein C, in Combination with Tissue Plasminogen...

Lyden P, Pryor KE, Coffey CS, Cudkowicz M, Conwit R, Jadhav A, Sawyer RN, Claassen J, Adeoye O, Song S, Hannon P, Rost NS, Hinduja A, Torbey M, Lee JM, Benesch C, Rippee M, Rymer M, Froehler MT, Haley EC, Johnson M, Yankey J, Magee K, Qidwai J, Levy H, Haacke EM, Fawaz M, Davis TP, Toga AQ, Griffin JH, Zlokovic BV, the NeuroNEXT Clinical Trials Network NN104 Investigators.
Annals of Neurology. 2019 January 7; 85 125-36.