Collaboration Among Pharmacists and Physicians to Improve Outcomes Now (CAPTION) was a collaboration with Dr. Barry Carter and Gail Ardery in the University of Iowa College of Pharmacy. CAPTION was a multi-center trial to determine the extent to which physician-pharmacist collaborative management (PPCM) of chronic disease state was adopted in clinics with geographic, racial, and ethnic diversity. The randomization of all clinic patients prior to screening decreased the selection bias and thereby increased the generalizability of the results. CAPTION focused on intervention effects among minority patients, and on how the study intervention was actually implemented at the study sites.