LRRK2 Cohort Consortium
The LRRK2 Cohort Consortium, funded by the Michael J. Fox Foundation, brought research groups together to speed efforts to move LRRK2 toward therapeutic relevance for patients. The CTSDMC served as...
PPMI
The Parkinson's Progression Markers Initiative (PPMI), funded by the Michael J. Fox Foundation, is a landmark observational clinical study to comprehensively evaluate cohorts of significant interest...
CAPTION
Collaboration Among Pharmacists and Physicians to Improve Outcomes Now (CAPTION) was a collaboration with Dr. Barry Carter and Gail Ardery in the University of Iowa College of Pharmacy. CAPTION was a...
Placebo-Controlled Trial of Sertraline and IPT for Postpartum Depression (ZIP)
The purpose of this study was to test the efficacy of sertraline and Interpersonal Psychotherapy (IPT) relative to pill placebo in a two site randomized controlled trial over a period of 12 weeks. It...
Bracing in Adolescent Idiopathic Scoliosis Trial (BrAIST)
BrAIST was a Phase II, multi-center, prospective randomized, partially blinded clinical trial designed to determine whether the use of thoracolumbosacral orthoses (TLSOs) lowers the risk of curve...
Clinical Islet Transplantation Consortium
The Clinical Islet Transplantation (CIT) Consortium, jointly supported by the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) and the National Institute of Allergy and...
Carotid Occlusion Surgical Study (COSS)
The Carotid Occlusion Surgery Study (COSS) was conducted to determine if superficial temporal artery-middle cerebral artery (STA-MCA) bypass, when added to the best medical therapy, would reduce...
Trial of Org10172 in Acute Stroke Treatment (TOAST)
Trial of Org10172 in Acute Stroke Treatment (TOAST) was the first large multi-center trial to be managed by the CTSDMC. The TOAST study began in 1989, and involved 42 participating clinical centers...